Harry Holthofer, Dublin City University

Research Focus:

Inflammation, innate & adaptive immunity, immune disorders, immunological mechanisms of renal disease and the respective immunological assays (including autoimmunity). Active links to diabetic nephropathy biobanks, genomic, transcriptomic and proteomic array methods

Relevance of your Provisional grouping in KidneyConnect:

Analysis of patients samples and development of new diagnostic techniques for renal diseases

Resources Available relevant to your grouping

  • Special Techniques: Light and electron microscopy, immunohistology, antibody and antigen assay techniques
  • Animal Models/Knock Outs: Nephrin knockout, conditional podocyte-specific
  • Datasets: Diabetic nephropathy (at FinnDiane; www.finndiane.fi); congenital nephrotic syndrome tissue biobank
  • Others

Clinical/Translational Resources

  • BiobanksĀ  Available at Biomedicum Helsinki
  • Population/Patient Cohorts
  • Access to patients with systemic rheumatic diseases (collaboration with the clinicians of Helsinki University Hospital)
  • Access to patients with IgA nephropathy (collaboration with the clinicians of Helsinki University Hospital)
  • APECED-patients with autoimmune interstitial nephritis

Special Techniques for Clinical Assessment

  • Patient Groups for Clinical trials
  • Others